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1

Post-partum haemorrhage and tranexamic acid: a global issue

Hibbs, Stephen P., Roberts, Ian, Shakur-Still, Haleema, Hunt, Beverley J.

Journal:

British Journal of Haematology

Year:

2018

Language:

english

File:

PDF, 393 KB

english, 2018

2

Tranexamic acid for treatment of women with post-partum haemorrhage in Nigeria and Pakistan: a cost-effectiveness analysis of data from the WOMAN trial

Li, Bernadette, Miners, Alec, Shakur, Haleema, Roberts, Ian

Journal:

The Lancet Global Health

Year:

2018

Language:

english

File:

PDF, 986 KB

english, 2018

3

The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo controlled trial

Haleema Shakur, Diana Elbourne, Metin Gülmezoglu, Zarko Alfirevic, Carine Ronsmans, Elizabeth Allen, Ian Roberts

Journal:

Year:

2010

Language:

english

File:

PDF, 929 KB

english, 2010

4

Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial

Katharine Ker, Junko Kiriya, Pablo Perel, Phil Edwards, Haleema Shakur, Ian Roberts

Journal:

BMC Emergency Medicine

Year:

2012

Language:

english

File:

PDF, 287 KB

english, 2012

5

Tranexamic acid for trauma – Authors' reply

Haleema Shakur, Ian Roberts, Pablo Perel

Journal:

Year:

2010

Language:

english

File:

PDF, 147 KB

english, 2010

6

Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial

Shakur, Haleema, Roberts, Ian, Fawole, Bukola, Chaudhri, Rizwana, El-Sheikh, Mohamed, Akintan, Adesina, Qureshi, Zahida, Kidanto, Hussein, Vwalika, Bellington, Abdulkadir, Abdulfetah, Etuk, Saturday,

Journal:

Year:

2017

Language:

english

File:

PDF, 1.55 MB

english, 2017

7

Hydroxyethyl starch solutions and patient harm

Roberts, Ian, Shakur, Haleema, Bellomo, Rinaldo, Bion, Julian, Finfer, Simon, Hunt, Beverley, Myburgh, John, Perner, Anders, Reinhart, Konrad

Journal:

Lancet (London, England)

Year:

2018

Language:

english

File:

PDF, 34 KB

english, 2018

8

Tranexamic acid through intravenous, intramuscular and oral routes: an individual participant data meta‐analysis of pharmacokinetic studies in healthy volunteers

Grassin‐Delyle, Stanislas, Semeraro, Michaela, Foissac, Frantz, Bouazza, Naim, Shakur‐Still, Haleema, Roberts, Ian, Treluyer, Jean‐Marc, Urien, Saïk

Journal:

Fundamental & Clinical Pharmacology

Year:

2019

Language:

english

File:

PDF, 578 KB

english, 2019

9

Giving tranexamic acid to reduce surgical bleeding in sub-Saharan Africa: an economic evaluation

Carla Guerriero, John Cairns, Sudha Jayaraman, Ian Roberts, Pablo Perel, Haleema Shakur

Journal:

Cost Effectiveness and Resource Allocation

Year:

2010

Language:

english

File:

PDF, 436 KB

english, 2010

10

The BRAIN TRIAL: a randomised, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury

Haleema Shakur, Peter Andrews, Toomas Asser, Laura Balica, Cristian Boeriu, Diego Ciro Juan Quintero, Yashbir Dewan, Patrick Druwé, Olivia Fletcher, Chris Frost, Bennie Hartzenberg, Jorge Mejia Mantil

Journal:

Year:

2009

Language:

english

File:

PDF, 242 KB

english, 2009

11

Response to: The BRAIN TRIAL: a randomized, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury - authors' reply

Ian Roberts, Haleema Shakur

Journal:

Year:

2009

Language:

english

File:

PDF, 153 KB

english, 2009

12

Managing clinical trials

Barbara Farrell, Sara Kenyon, Haleema Shakur

Journal:

Year:

2010

Language:

english

File:

PDF, 224 KB

english, 2010

13

European society of intensive care medicine study of therapeutic hypothermia (32-35°C) for intracranial pressure reduction after traumatic brain injury (the Eurotherm3235Trial)

Peter JD Andrews, Helen Louise Sinclair, Claire G Battison, Kees H Polderman, Giuseppe Citerio, Luciana Mascia, Bridget A Harris, Gordon D Murray, Nino Stocchetti, David K Menon, Haleema Shakur, Danie

Journal:

Year:

2011

Language:

english

File:

PDF, 1.25 MB

english, 2011

14

Using a business model approach and marketing techniques for recruitment to clinical trials

Alison M McDonald, Shaun Treweek, Haleema Shakur, Caroline Free, Rosemary Knight, Chris Speed, Marion K Campbell

Journal:

Year:

2011

Language:

english

File:

PDF, 348 KB

english, 2011

15

Marketing and clinical trials: a case study

David Francis, Ian Roberts, Diana R Elbourne, Haleema Shakur, Rosemary C Knight, Jo Garcia, Claire Snowdon, Vikki A Entwistle, Alison M McDonald, Adrian M Grant, Marion K Campbell

Journal:

Year:

2007

Language:

english

File:

PDF, 202 KB

english, 2007

16

Prognosis following head injury: a survey of doctors from developing and developed countries

Pablo Perel, Jonathan Wasserberg, Ramalingam R. Ravi, Haleema Shakur, Phil Edwards, Ian Roberts

Journal:

Journal of Evaluation in Clinical Practice

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

17

Use of the Oxford Handicap Scale at hospital discharge to predict Glasgow Outcome Scale at 6 months in patients with traumatic brain injury

Pablo Perel, Phil Edwards, Haleema Shakur, Ian Roberts

Journal:

BMC Medical Research Methodology

Year:

2008

Language:

english

File:

PDF, 207 KB

english, 2008

18

Anti-fibrinolytic agents in post partum haemorrhage: a systematic review

Pili Ferrer, Ian Roberts, Emma Sydenham, Karen Blackhall, Haleema Shakur

Journal:

BMC Pregnancy and Childbirth

Year:

2009

Language:

english

File:

PDF, 201 KB

english, 2009

19

The effect of the steroid-sparing response to low-dose methotrexate on bone metabolism in glucocorticoid-dependent asthmatics

Samia I. Girgis, Amanda Nwokeji, B.Haleema Shakur, Philip W. Ind, Robert J. Shiner

Journal:

Clinica Chimica Acta

Year:

2004

Language:

english

File:

PDF, 228 KB

english, 2004

20

Covariate adjustment increased power in randomized controlled trials: an example in traumatic brain injury

Elizabeth L. Turner, Pablo Perel, Tim Clayton, Phil Edwards, Adrian V. Hernández, Ian Roberts, Haleema Shakur, Ewout W. Steyerberg

Journal:

Journal of Clinical Epidemiology

Year:

2012

Language:

english

File:

PDF, 221 KB

english, 2012

21

Effect of consent rituals on mortality in emergency care research

Ian Roberts, David Prieto-Merino, Haleema Shakur, Iain Chalmers, Jon Nicholl

Journal:

Year:

2011

Language:

english

File:

PDF, 94 KB

english, 2011

22

Consent in emergency care research – Authors' reply

Ian Roberts, Iain Chalmers, Haleema Shakur, David Prieto-Merino, Jon Nicholl

Journal:

Year:

2011

Language:

english

File:

PDF, 79 KB

english, 2011

23

Early administration of tranexamic acid in trauma patients – Authors' reply

Ian Roberts, David Prieto-Merino, Pablo Perel, Haleema Shakur

Journal:

Year:

2011

Language:

english

File:

PDF, 41 KB

english, 2011

24

Improving outcomes for patients with traumatic brain injury: The CRASH-3 trial in India

Haleema Shakur, Yashbir Dewan

Journal:

The Indian Journal of Neurotrauma

Year:

2012

Language:

english

File:

PDF, 159 KB

english, 2012

25

A promise to save 100 000 trauma patients

Haleema Shakur, Ian Roberts, Peter Piot, Richard Horton, Etienne Krug, Jeannot Mersch

Journal:

Year:

2013

Language:

english

File:

PDF, 114 KB

english, 2013

26

Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease

Nicholas W Morrell, Matthew A Higham, Peter G Phillips, B Haleema Shakur, Paul J Robinson, Ray J Beddoes

Journal:

Respiratory Research

Year:

2005

Language:

english

File:

PDF, 547 KB

english, 2005

27

CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial

Yashbir Dewan, Edward O Komolafe, Jorge H Mejía-Mantilla, Pablo Perel, Ian Roberts, Haleema Shakur

Journal:

Year:

2012

Language:

english

File:

PDF, 979 KB

english, 2012

28

The death knell for academic led clinical trials in India?

Dewan, Yashbir, Shakur, Haleema, Kawahara, Taemi, Dua, Sanjeev

Journal:

The Indian Journal of Neurotrauma

Year:

2013

Language:

english

File:

PDF, 187 KB

english, 2013

29

Good clinical practice in trauma care research: Considerations for inter-hospital patient transfers

Bryceland, Catriona, Ellis, Sophie, Beaumont, Danielle, Shakur, Haleema, Coats, Timothy J.

Journal:

International Emergency Nursing

Year:

2015

Language:

english

File:

PDF, 174 KB

english, 2015

30

HALT-IT - tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial

Roberts, Ian, Coats, Timothy, Edwards, Phil, Gilmore, Ian, Jairath, Vipul, Ker, Katharine, Manno, Daniela, Shakur, Haleema, Stanworth, Simon, Veitch, Andrew

Journal:

Year:

2014

Language:

english

File:

PDF, 1.43 MB

english, 2014

31

Comparative effectiveness, safety and acceptability of medical abortion at home and in a clinic: a systematic review

Ngo, Thoai D, Park, Min Hae, Shakur, Haleema, Free, Caroline

Journal:

Bulletin of the World Health Organisation

Year:

2011

Language:

english

File:

PDF, 645 KB

english, 2011

32

Antifibrinolytic Agents in Traumatic Haemorrhage

Coats, Tim, Hunt, Beverly, Roberts, Ian, Shakur, Haleema

Journal:

Year:

2005

Language:

english

File:

PDF, 167 KB

english, 2005

33

The CRASH2 trial: the first 1000 patients

Coats, Timothy, Beverley, Hunt, Haleema, Shakur, Ian, Roberts

Journal:

European Journal of Emergency Medicine

Year:

2006

Language:

english

File:

PDF, 87 KB

english, 2006

34

Prognostic Value of Major Extracranial Injury in Traumatic Brain Injury

van Leeuwen, Nikki, Lingsma, Hester F., Perel, Pablo, Lecky, Fiona, Roozenbeek, Bob, Lu, Juan, Shakur, Haleema, Weir, James, Steyerberg, Ewout W., Maas, Andrew I.R.

Journal:

Year:

2012

Language:

english

File:

PDF, 210 KB

english, 2012

35

The effect of tranexamic acid on the risk of death and hysterectomy in women with post-partum haemorrhage: statistical analysis plan for the WOMAN trial

Shakur, Haleema, Roberts, Ian, Edwards, Philip, Elbourne, Diana, Alfirevic, Zarko, Ronsmans, Carine

Journal:

Year:

2016

Language:

english

File:

PDF, 768 KB

english, 2016

36

Does tranexamic acid improve outcomes in traumatic brain injury?

Mahmood, Abda, Roberts, Ian, Shakur, Haleema, Harris, Tim, Belli, Antonio

Journal:

Year:

2016

Language:

english

File:

PDF, 1005 KB

english, 2016

37

Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms

Roberts, Ian, Edwards, Phil, Prieto, David, Joshi, Miland, Mahmood, Abda, Ker, Katharine, Shakur, Haleema

Journal:

Year:

2017

Language:

english

File:

PDF, 656 KB

english, 2017

38

A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding Mechanistic Sub-Study [CRASH-3 IBMS])

Mahmood, Abda, Roberts, Ian, Shakur, Haleema

Journal:

Year:

2017

Language:

english

File:

PDF, 945 KB

english, 2017

39

Tranexamic acid for post-partum haemorrhage in the WOMAN trial – Authors' reply

Roberts, Ian, Shakur, Haleema

Journal:

Lancet (London, England)

Year:

2017

Language:

english

File:

PDF, 39 KB

english, 2017

40

Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients

Gayet-Ageron, Angèle, Prieto-Merino, David, Ker, Katharine, Shakur, Haleema, Ageron, François-Xavier, Roberts, Ian, Kayani, Aasia, Geer, Amber, Ndungu, Bernard, Fawole, Bukola, Gilliam, Catherine, Ade

Journal:

Lancet (London, England)

Year:

2017

Language:

english

File:

PDF, 1.17 MB

english, 2017

41

Haemostatic drugs for traumatic brain injury

Perel, Pablo, Roberts, Ian, Shakur, Haleema, Thinkhamrop, Bandit, Phuenpathom, Nakornchai, Yutthakasemsunt, Surakrant

Journal:

Cochrane database of systematic reviews

Year:

2015

Language:

english

File:

PDF, 76 KB

english, 2015

42

Antifibrinolytic drugs for treating primary postpartum haemorrhage

Shakur, Haleema, Beaumont, Danielle, Pavord, Sue, Gayet-Ageron, Angele, Ker, Katharine, Mousa, Hatem A

Journal:

Cochrane database of systematic reviews

Year:

2018

Language:

english

File:

PDF, 817 KB

english, 2018

43

Haematological and fibrinolytic status of Nigerian women with post-partum haemorrhage

Roberts, Ian, Shakur, Haleema, Fawole, Bukola, Kuti, Modupe, Olayemi, Oladapo, Bello, Adenike, Ogunbode, Olayinka, Kotila, Taiwo, Aimakhu, Chris O., Olutogun, Tolulase, Hunt, Beverley J., Huque, Sumay

Journal:

BMC Pregnancy and Childbirth

Year:

2018

Language:

english

File:

PDF, 911 KB

english, 2018

44

What women think about consent to research at the time of an obstetric emergency: A qualitative study of the views of a cohort of World Maternal Antifibrinolytic (WOMAN) Trial participants

Houghton, Gillian, Kingdon, Carol, Dower, Michelle, Shakur-Still, Haleema, Alfirevic, Zarko

Journal:

BJOG: An International Journal of Obstetrics & Gynaecology

Year:

2018

Language:

english

File:

PDF, 886 KB

english, 2018

45

Cost-Effectiveness Analysis of Administering Tranexamic Acid to Bleeding Trauma Patients Using Evidence from the CRASH-2 Trial

Guerriero, Carla, Cairns, John, Perel, Pablo, Shakur, Haleema, Roberts, Ian, Eltzschig, Holger K.

Journal:

Year:

2011

Language:

english

File:

PDF, 210 KB

english, 2011

46

Should hydroxyethyl starch be banned? – Authors' reply

Roberts, Ian, Shakur, Haleema, Bellomo, Rinaldo, Bion, Julian, Finfer, Simon, Hunt, Beverley, Myburgh, John, Perner, Anders, Reinhart, Konrad

Journal:

Lancet (London, England)

Year:

2018

Language:

english

File:

PDF, 116 KB

english, 2018

47

Risk factors for peripartum hysterectomy among women with postpartum haemorrhage: analysis of data from the WOMAN trial

Huque, Sumaya, Roberts, Ian, Fawole, Bukola, Chaudhri, Rizwana, Arulkumaran, Sabaratnam, Shakur-Still, Haleema

Journal:

BMC Pregnancy and Childbirth

Year:

2018

Language:

english

File:

PDF, 620 KB

english, 2018

48

Finding Better Ways to Prevent Postpartum Hemorrhage

Shakur-Still, Haleema, Roberts, Ian

Journal:

New England Journal of Medicine

Year:

2018

File:

PDF, 67 KB

2018

49

The impact of early outcome events on the effect of tranexamic acid in post-partum haemorrhage: an exploratory subgroup analysis of the WOMAN trial

Brenner, Amy, Shakur-Still, Haleema, Chaudhri, Rizwana, Fawole, Bukola, Arulkumaran, Sabaratnam, Roberts, Ian

Journal:

BMC Pregnancy and Childbirth

Year:

2018

Language:

english

File:

PDF, 849 KB

english, 2018

50

Finding Better Ways to Prevent Postpartum Hemorrhage

Shakur-Still, Haleema, Roberts, Ian

Journal:

New England Journal of Medicine

Year:

2018

Language:

english

File:

PDF, 67 KB

english, 2018

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